Dermeca Plla 400mg-Restore natual collagen

Dermeca Plla is used to correct shallow to deep nasolabial contour defects and other problems, correct fine lines and wrinkles in the cheek area, restore lost fat to the face, and correct signs of facial lipoatrophy.

DERMECA PLLA is a Poly-L-Lactic Acid (PLLA) -based filler that stimulates the skin's collagenproduction, effectively diminishing the look of fine lines and wrinkles. PLLA ensures long-lastinganti-wrinkle effects, with skin looking tight and fuller for 18 ~ 24 months. Upon injection, the PLAparticles work to replace lost collagen and reinforce the skin structure. Over time, the appearance of fine lines and wrinkles will decrease as the skin's collagen levels increase Your skin gradually becomes smoother and looks rejuvenated, with results lasting up to 2 years after the injection.

• Instant dissolvingin 10 seconds.
DERMECA PLLA uses a series of patented technologiesto produce solid microspheres with uniform size andsmooth surface. Not only do they not require long-termre-dissolution like traditional baby face needles, whichincreases the risk of infection, but they can also avoidthe formation of foam. These bubbles contain someagglomerations of particles, which may not only clogthe needle but also increase the risk of nodules.

• High Purity to obviouslyimprove the stimulating effect while lower the side efects.
The advantage of DERMECA PLLA in raw materials is the "selectivity of the catalyst". Tiera'spatent is to ensure that only left-handed polylactic acid is polymerized in the process of raw mate.rial manufacturing, but not right-handed polylactic acid. In order to obtain high-purity poly-Llactic acid, it is ensured that only poly-L-lactic acid is produced from the raw materials from thebeginning. This patented technology is called-multi-center stereo composite catalytic technology which greatly improves the purity of poly-L-lactic acid.

• Uniform degradation rate and stable clinical effect.
Solid microspheres can also maintain long-term stable effects for two years. Other Korean PLLAinjections use porous microsphere structures that degrade quickly, while DERMECA PLLA degrades in its entirety, which means that the inside and outside of the product degrade together, so that the degradation rate of DERMECA PLLA’s can be controlled to be uniform, and the microsphere structure lasts longer, with a more sustained effect.

• Preparation before operation (mix-shake-push-divide)

Step1 Open the bottle and disinfect.Open the cap of the syringe bottle and clean the rubber stopper with a disinfectant cotton pad.

Step2 Mix the medicine.01. Use a 5ml (or 10ml) syringe to extract 4ml (appropriate dosage according to the operation site) ofnormal saline.02.Tilt the bottle and inject the normal saline to prevent bubbles in the liquid.

Step3 Fully Hydration.01.Shake moderately for 10-15 seconds to ensure that the lyophilized powder is completely hydrated.

Step4 Add Lidocaine.Add an appropriate amount oflidocaine (appropriate dosage according to the operation site ) and mix it evenly with the previously hydrated medicine.

Step5 Ouantityasneeded.Put the mixed liquid into a lml syringe and use it as needed.

Potential Adverse Events

• Reaction to theinjection sites-Hemorrhage-Pain-Induration -Swelling.

• Abnormalityto theimmune system-Hypersensitivity Angioedema-Skin sarco dosis.

• Inflammation andinfection-Infection ofthe injection sitesincuding facial cellulitis-Staphylococcal infection-Abscess at theinjection sites.

• Abnormalityin skin and subcutaneous tissue-Bruising-Hematoma.

• Atrophy or skin hypertrophy at theinjection sites-Erythema at theinjection sites-Urticaria at theinjec-tion sites -Telangiectasis.

• Most papules in the subcutaneous tissue can be sensed by palpation,but they are not visible,and have nosymptom.

• After treatment,nodulesincludingperiorbital nodu-les can be visible,and those nodules may be accompa-nied by inflammation or discoloration.Nodules under the skin detected at the inital stage ofinjection can beminimized by adequate dilution andinjection.-Nodules under the skin may be apparent later (withinone through 14 months after injection),and may lastfor two years,it may be necessary to remove nodulesvoluntarily,surgically,or bythetreatmentofintralesional corticosteroids-Granuloma-Scarring-Skin discoloration.


General Precautions

• The treatment with this product should be done by aspecialist doctorwho has completed necessary training.

• Before injectingthis product to patients,explain pr-ecisely to the patients the indications ofthis product,prohibitions ,and potential side effects.

• Before usingthe product,make sure whether the st-erile condition is damaged or contaminated.

• Check the validity on the product label.

• Theinjection sites should be cleaned with antisepticgauzes,and havenoinflammation orinfection.

• Instruct the patients after beinginjected by this pro-duct to pay more attention to their injection sites inorder to minimize the exposure to the sunlight,and notto be exposed Ultraviolet (UV) lamps until swellingandredness at the initial stage of the Injection will disapp-ear.

• Since the treatment effects take place gradually we-eks afterinjection, do not over-inject at the same sites.

• Untilinfection and inflammation is controlled or se-ttle down, do not use the product.


Interaction

No research has been done on the interaction ofthis pr-oduct with other drugs,components,and implants



Cautions duringTreatment

• Be cautious snce it is reported tha the risk of causingpapules or nodulesMay be increased by injection wheninjectinginto the sites of thin skin likeperiorbital areas,over-injetion and wrong compounding of the solution.The occurrence of papules or nodules can be minimizedby massaging The injection sites to evenly spread theinjected product.

• Do not inject into the vermillion areas oflips.

• Avoid the injection into blood vessels which may causevesselocclusion and the subsequent tissue necrosis.